Published: 10/02/2013 - Updated: 11/05/2018
Better detection methods: Although celiac disease often presents as a difficulty for those who suffer unknowingly, today we can say that coming to an encouraging respect.
Because most of the players has gone through numerous studies and analysis to achieve bowel biopsy confirmed the disease. And in this screening process has led, for many, many years.
The steps to follow to make th diagnosis that are currently consist of a serological test to detect the presence of antibodies specific to celiac disease, beter detection, particularly IgA class anti-tissue transglutaminase (tTG). Furthermore, also the value of IgG antibodies anti-tissue transglutaminase as the patient shows IgA deficiency (detected by analyzing the levels of total IgA). The positive result of serological test involves making an intestinal biopsy, which is to draw several samples from the duodenal-jejunal area to see if there is damage to the villi. In cases where the symptoms of celiac disease are also very clear is if the biopsy results from the serological test is negative.
Detection Methods: Novelty: a diagnostic chip
Well, the novelty is that in the future, the detection methods: A ‘chip’ can diagnose celiac disease through a blood sample, and reliable way without having to perform an intestinal biopsy in the person. The news was announced by members of the General Assembly II Project ‘Celiac Disease-Management, Monitoring and Diagnosis using Biosensors and an Integrated Sytem Chip’ (CD-MEDICS), the consortium responsible for developing this microsystem.
According to the director of the Celiac Association of Madrid, Manuel Marquez, is a disposable cartridge for the diagnosis of micro-fluidics intelligent, non-invasive and low cost in primary care (AP) containing test reagents and sensors for the primary diagnosis and monitoring of the disease. The cartridge is inserted and controlled by an instrument that will analyze data from sensors and provide information to clinicians in a short time, “he explained. Marquez said that is funded by the European Union with 9.5 million, up nearly 13 million funding is private. He also underlined that “this system will have an impact for celiac,” since the change in number and collective demands that are made for years will therefore have more hearing before the agency.
For its part, the project director and researcher at the University Rovira i Virgili, Ciara O’Sullivan explained that this instrument will be capable of operating in the same way in any environment patient care and communicate the results clearly with existing information systems in hospitals, as well as update the electronic monitoring of the patient in a hospital.“When patients go to an analysis done at the doctor’s office can update the results in an electronic archive, and watch the levels of antibodies for years and have a history,” said this expert. In the operation, explained that this is a simple method, since “the chip is inserted inside the 15 minutes and the analysis is done.”
According to O’Sullivan, already owns the design of the ‘chip’ and the device, which will be produced shortly and is expected to be available in the market over the next five years. In addition, biobanks have been established – where the show’s serum or blood for analysis – have been set up courses to train doctors and brochures describing the disease. “The first thing is to train doctors in AP,” he said.
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